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| Pivotal study confirms potential of Novartis candidate vaccine Bexsero to help protect infants against meningococcal serogroup B disease |
| The Journal of the American Medical Association (JAMA) published a study that shows Bexsero induced a robust immune response against meningococcal B disease in the vast majority of infants vaccinated. These results also show that Bexsero can fit into various vaccination schedules in the first year o... |
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| Pepscan Therapeutics achieves milestones in research collaboration with Janssen R&D Irelad |
| Pepscan Therapeutics B.V. announced that it has achieved two milestones in the Research Collaboration with Janssen R&D Ireland, formerly Tibotec Pharmaceuticals, and received undisclosed payments. In the collaboration, Pepscan has discovered novel peptides with potential therapeutic utility using i... |
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| arGEN-X advances third therapeutic antibody program into preclinical development |
| arGEN-X announced that it has progressed ARGX-111, its third therapeutic candidate, into formal preclinical development.ARGX-111 is a novel, fully human antibody specific for c-Met, a receptor tyrosine kinase involved in cell proliferation, angiogenesis and metastasis. c-Met is widely implicated in ... |
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| Good timing: NIST/CU collaboration adds timing capability to living cell sensors |
| Individual cells modified to act as sensors using fluorescence are already useful tools in biochemistry, but now they can add good timing to their resumé, thanks in part to expertise from the National Institute of Standards and Technology (NIST).With the added capability to track the timing of dynam... |
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| Bio-disinfection with semi-composted manure to control a pepper crop disease |
| Researchers at the Basque Institute for Agricultural Research and Development, Neiker-Tecnalia, have confirmed that the use of semi-composted manure in combination with the plastic sealing of the soil is an effective control for Phytophthora capsici, a fungus responsible for a disease that seriously... |
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| The Myelin Repair Foundation and ENDECE Neural Form Collaboration to Develop Myelin Regenerative Compounds for Multiple Sclerosis (MS) Treatment |
| The Myelin Repair Foundation (MRF) and ENDECE Neural, LLC have formed a partnership to expedite the advancement of myelin regeneration drug candidates for Multiple Sclerosis (MS) patients through pre-clinical studies and into Phase I clinical studies.Through this collaboration, the newly launched MR... |
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| New production method could fill major need for new sources of MSCs |
| Stem cell scientists from the University of Queensland Centre for Clinical Research (UQCCR) in Australia have discovered a new method for producing mesenchymal stem/stromal cells (MSCs) from human iPSCs that substantially improves on current methods and speeds up conversion time. The research, publi... |
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| Sistemic to Work with TiGenix On FP7 European Project Aiming at Developing an Innovative Rheumatoid Arthritis Cell Therapy Treatment Product |
| Sistemic announced that its proprietary technology (SistemQC™) has been chosen to form a key part of the research and production process for a landmark multinational collaborative project led by TiGenix, Belgium and including partners from Spain, France, the Netherlands as well as the UK and Belgium... |
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| Pieris Receives BMBF Grant to Fund PRS-110 c-Met Antagonist Anticalin Program |
| Pieris AG announced the receipt of a EUR 1 million grant to support the development of the company’s proprietary PRS-110 compound targeting c-Met, a cellular receptor that plays a key role in cancer cell growth and metastasis. The goal of the funded research will be to delineate a biomarker strategy... |
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| New study sheds light on genetics of rice metabolism |
| A large-scale study analyzing metabolic compounds in rice grains conducted by researchers at the RIKEN Plant Science Center (PSC) and their collaborators has identified 131 rice metabolites and clarified the genetic and environmental factors that influence their production. The findings provide a na... |
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| Increased crop yield through better insight in molecular networks |
| The VIB Department for Plant Systems Biology at Ghent University and BASF Plant Science announced a cooperation agreement in plant biotechnology. Together they will develop a novel technology to identify genes and gene networks that control crop yield. The project, designated TopYield, will explore ... |
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| Parkinson's disease: Study of live human neurons reveals the disease's genetic origins |
| Parkinson's disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease. The results are published in Nature Communications.The UB findings reveal potential new drug targets for the disease as well as a screening platform for discovering new tr... |
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| caprotec bioanalytics Announces Further Patent Protection Of Its CCMS Technology |
| caprotec bioanalytics GmbH announced the issuance of patents in the US, Japan, Canada, Australia and Israel related to methods and composition of matter of its proprietary Capture Compound Mass Spectrometry (CCMS) technology.Issued US Patent US 7,858,560 titled “Capture Compounds, Collections thereo... |
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| Developing countries lead the way in the global adoption of biotech crops |
| Globally, it is clear that since the first commercial planting in 1996, biotech crops have become an integral part of farming’s present and future, and developing countries are now leading the way. In 2011, developing countries adopted biotech crops at twice the rate of developed countries. Moreove... |
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| Major Expansion for Brecon Pharmaceuticals |
| Brecon Pharmaceuticals announces the expansion of its storage and distribution capacity, with investment in a state-of-the-art, purpose-built facility in South Wales, UK. Responding to customer demand the new site will provide a further 23,000 square feet of temperature-controlled storage facilities... |
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| Clinuvel files European marketing authorisation application for SCENESSE (afamelanotide) |
| Clinuvel Pharmaceuticals Limited announced that it has submitted a marketing authorisation application (MAA) for its first-in-class drug SCENESSE® (afamelanotide 16mg implant) to the European Medicines Agency (EMA). The MAA covers the use of SCENESSE® as a prophylactic treatment in adult patients wi... |
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| Valeant Pharmaceuticals Completes Divestiture of Generic Dermatology Products to Mylan |
| Valeant Pharmaceuticals International, Inc. announced that it has completed the divestiture of 1% clindamycin and 5% benzoyl peroxide gel (IDP-111), a generic version of Benzaclin, and 5% fluorouracil cream, (5-FU), an authorized generic of Efudex, to Mylan Inc.. This action was required under the c... |
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| Heart hormone helps shape fat metabolism |
| It's well known that exercising reduces body weight because it draws on fat stores that muscle can burn as fuel. But a new study at Sanford-Burnham Medical Research Institute (Sanford-Burnham) suggests that the heart also plays a role in breaking down fat. In their study, published in the Journal of... |
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| Sharp images from the living mouse brain |
| To explore the most intricate structures of the brain in order to decipher how it functions – Stefan Hell's team of researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen has made a significant step closer to this goal. Using the STED microscopy developed by Hell, the scienti... |
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| Metabolic 'breathalyzer' reveals early signs of disease |
| The future of disease diagnosis may lie in a "breathalyzer"-like technology currently under development at the University of Wisconsin-Madison. New research published in Metabolism demonstrates a simple but sensitive method that can distinguish normal and disease-state glucose metabolism by a quick ... |
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| Genes linked to cancer could be easier to detect with liquid lasers |
| Using a liquid laser, University of Michigan researchers have developed a better way to detect the slight genetic mutations that might predispose a person to a particular type of cancer or other diseases. Their results are published in Angewandte Chemie. This work could advance understanding of the ... |
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| Celgene Executive Dr Rajesh Chopra joins the Board of e-Therapeutics |
| e-Therapeutics plc announced that Dr Rajesh Chopra has joined the Company’s Board as a Non-Executive Director. A clinician and scientist by training, Dr Chopra has since 2009 been Vice President of Translational and Early Drug Development at Celgene Corporation. He leads a group of around 100 people... |
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| Pushing the Boundaries: New dye could open the door to in vivo applications of fluorescence anisotropy |
| US scientists have synthesized a polymethine dye that can be used for fluorescence anisotropy imaging in the near-infrared (NIR) spectral range, making new in vivo applications of this technique possible. Until now, the method has been limited to the visible part of the spectrum, mainly being used i... |
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| Pesticides keep fungus poisons out of the food chain |
| Farmers must control fungus to keep food safe is the main conclusion of a new study presented at the DG SANCO’s Fusarium Forum. The study, carried out by Horta Srl. and the University of Piacenza “Università Cattolica del Sacro Cuore”, stresses the importance of the azole class of fungicides in the... |
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| Steroids control gas exchange in plants |
| Plants leaves are sealed with a gas-tight wax layer to prevent water loss. Plants breathe through microscopic pores called stomata (Greek for mouths) on the surfaces of leaves. Over 40% of the carbon dioxide, CO2, in the atmosphere passes through stomata each year, as well a water volume twice that ... |
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| Chemists develop faster, more efficient protein labeling |
| North Carolina State University researchers have created specially engineered mammalian cells to provide a new "chemical handle" which will enable researchers to label proteins of interest more efficiently, without disrupting the normal function of the proteins themselves or the cells in which they ... |
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| Eppendorf & Science Prize for Neurobiology 2012 |
| Eppendorf and the world-renowned journal Science are now accepting applications for the 2012 Eppendorf & Science Prize for Neurobiology. The Eppendorf & Science Prize for Neurobiology is an annual international research prize of US$ 25,000. It is awarded to one young scientist for his or her outstan... |
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| Katja Stolle takes over as analytica Exhibition Director |
| Effective February 6, 2012, Katja Stolle (31) will be the interim head of the Exhibition Management team for analytica, the International Trade Fair for Laboratory Technology, Analysis and Biotechnology. Stolle is standing in for Susanne Grödl (42), who has been Exhibition Director of analytica sinc... |
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| From plants to plastics |
| Funded by the Knowledge Based Bio Economy program of the EU, the 13 M€ BioConSepT project starts in February 2012. The project wants to convince and inspire stakeholders of the Bio-based Economy by demonstrating the complete feasibility of an integrated chain approach, which is regarded as the basis... |
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| Ocean Optics Names Winner of 2012 Young Investigator Award |
| Ocean Optics has named Nathan J. Withers the winner of the SPIE 2012 Young Investigator Award sponsored by the company.The Young Investigator Award is presented to a researcher who is no more than five years out of school and submits the best juried paper as part of the Colloidal Nanocrystals for Bi... |
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| Prosonix Appoints Respiratory Drug Development Expert Dr Geoff Down as Chief Medical Officer |
| Prosonix announced the appointment of Dr Geoff Down to the newly created role of Chief Medical Officer. Dr Down takes up his position immediately and will oversee the clinical development of Prosonix’s product pipeline, including PSX1001, PSX1002 and the novel PSX2000 combination series.Dr Down has ... |
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| Merck and Threshold Announce Global Agreement to Co-Develop and Commercialize Phase III Hypoxia-Targeted Drug TH-302 |
| Merck KGaA announced that a global agreement was signed with Threshold Pharmaceuticals, Inc. to co-develop and commercialize TH-302, Threshold’s small molecule hypoxia-targeted drug. TH-302 is currently being investigated in a global Phase III clinical trial in patients with soft tissue sarcoma, a r... |
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| Valeant Pharmaceuticals Acquires Probiotica in Brazil |
| Valeant Pharmaceuticals International, Inc. announced that Valeant has acquired Probiotica Laboratorios Ltda. Probiotica currently markets a full line of over-the-counter sports nutrition products and other food supplements, with a 30 percent share of the market. Valeant will acquire Probiotica for ... |
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| Dr. Stefan Arnold – new CSO completes executive board of instrAction |
| Dr. Stefan Arnold is the new Chief Scientific Officer and member of the executive board at InstrAction GmbH Ludwigshafen. In this function, he is responsible for product development and manufacture of novel agent-specific (both chemical and biological active ingredients and agents) affinity matrices... |
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| Understanding how bacteria come back from the dead |
| Salmonella remains a serious cause of food poisoning in the UK and throughout the EU, in part due to its ability to thrive and quickly adapt to the different environments in which it can grow. New research involving a team of IFR scientists, funded by BBSRC, has taken the first detailed look at what... |
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| Identical twins reveal mechanisms behind aging |
| In a recent study led by Uppsala University, the researchers compared the DNA of identical (monozygotic) twins of different age. They could show that structural modifications of the DNA, where large or small DNA segments change direction, are duplicated or completely lost are more common in older pe... |
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| Sartorius grows at double-digit rates and boosts operating earnings by more than 30% |
| Sartorius grew dynamically yet again in 2011 and significantly expanded its profitability. Both Group divisions reported highs in sales revenue and earnings. The financial targets that the company had raised twice before year-end were fully achieved. Sartorius expects positive business development f... |
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| Evocatal and RohnerChem announce strategic partnership for enzymatic chemistry development and upscaling |
| Evocatal and RohnerChem combine their complementary services to offer customers a seamless solution for the development of high-performance biocatalytic processesand their rapid application in the synthesis of fine chemicals and API. The focus of this strategic partnership is to offer highly innovat... |
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| Targeting tumors may help stop spread of breast, other cancers |
| Cancer that has spread from the site of an original tumor to other places in the body is often viewed as a death sentence. But if there are just a few of those secondary tumors, called metastases, some patients have a good chance of survival if treated with a type of radiation that precisely targets... |
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| Novozymes Biopharma wins Technology Innovation award for half-life extension platform |
| Novozymes Biopharma, part of Novozymes A/S, announced it has received the 2012 Drug Delivery Partnerships™ (DDP) Technology Innovation award for the company’s half-life extension platform. The albumin based technology platform offers the potential to enhance patient quality of life through tailoring... |
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| OctoPlus enters into drug development and manufacturing contract with Ferring Pharmaceuticals A/S |
| OctoPlus N.V. announced that a formulation development and manufacturing contract has been signed with Ferring Pharmaceuticals A/S. The undisclosed contract value will make a material contribution to OctoPlus' 2012 revenues. Further details on the compound and activities are not disclosed.... |
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| Athersys Awarded $3.6 Million in Grant Funding For Stem Cell Product Development |
| Athersys, Inc. announced grant funding aggregating $3.6 million to further advance its MultiStem® product programs and cell therapy platform. Specifically, Athersys was awarded a SBIR Fast-Track grant of up to $1.9 million from the National Institute of Neurological Disorders and Stroke (NINDS) to... |
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| Ablynx receives another milestone as Boehringer Ingelheim selects Nanobody candidate for pre-clinical development |
| Ablynx announced that Boehringer Ingelheim has selected, as part of their strategic alliance, a second Nanobody® candidate for pre-clinical development, which triggered a €5 million milestone payment to Ablynx. The Nanobody development candidate is designed to interfere with the function of two dist... |
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| Intercell announces positive results from two clinical Phase III studies supporting pediatric label extension of JE vaccine for children traveling to endemic areas |
| Intercell AG announced the successful completion of a pivotal Phase III trial in 1869 children conducted in the Philippines and favorable interim data from a second Phase III trial in EU, US and Australia. Analysis of both studies showed that the vaccine was well tolerated and immunogenic in childr... |
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| EUR 1.0 Million Grant Awarded to Exosome Diagnostics and Ludwig Maximilian University from German Federal Ministry for Education and Research to Develop Biofluid-Derived Exosome Diagnostics |
| Exosome Diagnostics GmbH, a subsidiary of Exosome Diagnostics, Inc., and the Department of Dermatology at the Ludwig Maximilian University (LMU) announces the awarding of a EUR one million grant from the German Federal Ministry for Education and Research (BMBF) to develop blood-based diagnostic test... |
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| European Thrombosis Therapeutics Market is Experiencing an Urgent Need for Enhanced Products, Says Frost & Sullivan |
| The increasing incidence of thrombosis, paralleled by the maturing life cycles of existing products, are motivating the need for novel alternatives. Establishing end-user confidence and ensuring cost-effectiveness pose significant challenges to market advancement. However, the launch of three blockb... |
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| New technology allows scientists to watch cancer cells in action at unprecedented resolution |
| A photograph of a polar bear in captivity, no matter how sharp the resolution, can never reveal as much about behavior as footage of that polar bear in its natural habitat. The behavior of cells and molecules can prove even more elusive. Limitations in biomedical imaging technologies have hampered a... |
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| Thermo Fisher Scientific Awarded Patent for Cell Factory System |
| Thermo Fisher Scientific Inc. announced that it has been awarded a patent by the United States Patent and Trademark Office on its Thermo Scientific Nunc Cell Factory System with Active Gassing, recognizing the device’s unique gas distribution system. Developed for cells that require a high or low le... |
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| Takara Bio Europe Goes Direct in 2012 |
| Takara Bio Europe announced that it will start selling its range of Takara brand products exclusively and directly to customers in the UK, Germany, Austria and Switzerland, with immediate effect. The decision means customers will be able to buy both Takara and Clontech brand products from one provid... |
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| Norovirus is the leading cause of infection outbreaks in U.S. hospitals |
| Norovirus, a pathogen that often causes food poisoning and gastroenteritis, was responsible for 18.2 percent of all infection outbreaks and 65 percent of ward closures in U.S. hospitals during a two-year period, according to a new study published in the American Journal of Infection Control (AJIC), ... |
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